REV1 and polymerase ζ facilitate homologous recombination repair

REV1 and DNA Polymerase ζ (REV3 and REV7) play important roles in translesion DNA synthesis (TLS) in which DNA replication bypasses blocking lesions. REV1 and Polζ have also been implicated in promoting repair of DNA double-stranded breaks (DSBs). However, the mechanism by which these two TLS polyme...

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Autores principales: Sharma, Shilpy, Hicks, J. Kevin, Chute, Colleen L., Brennan, Julia R., Ahn, Joon-Young, Glover, Thomas W., Canman, Christine E.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2012
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258153/
https://ncbi.nlm.nih.gov/pubmed/21926160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr769
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