Identification and characterization of Hoxa9 binding sites in hematopoietic cells

The clustered homeobox proteins play crucial roles in development, hematopoiesis, and leukemia, yet the targets they regulate and their mechanisms of action are poorly understood. Here, we identified the binding sites for Hoxa9 and the Hox cofactor Meis1 on a genome-wide level and profiled their ass...

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Autores principales: Huang, Yongsheng, Sitwala, Kajal, Bronstein, Joel, Sanders, Daniel, Dandekar, Monisha, Collins, Cailin, Robertson, Gordon, MacDonald, James, Cezard, Timothee, Bilenky, Misha, Thiessen, Nina, Zhao, Yongjun, Zeng, Thomas, Hirst, Martin, Hero, Alfred, Jones, Steven, Hess, Jay L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2012
Materias:
Hematopoiesis and Stem Cells
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257007/
https://ncbi.nlm.nih.gov/pubmed/22072553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-03-341081
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