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HOX Proteins and Leukemia

HOX and three amino acid loop extension (TALE) proteins cooperate to induce transformation in mouse leukemia models, and are dysregulated in a variety of human leukemias. Despite decades of research, the mechanism of action for Hox proteins in embryogenesis and hematopoiesis remains unclear. Recent...

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Détails bibliographiques
Auteurs principaux: Sitwala, Kajal V., Dandekar, Monisha N., Hess, Jay L.
Format: Artigo
Langue:Inglês
Publié: e-Century Publishing Corporation 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2480589/
https://ncbi.nlm.nih.gov/pubmed/18787682
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