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LRP6 Protein Regulates Low Density Lipoprotein (LDL) Receptor-mediated LDL Uptake
Genetic variations in LRP6 gene are associated with high serum LDL cholesterol levels. We have previously shown that LDL clearance in peripheral B-lymphocytes of the LRP6(R611C) mutation carriers is significantly impaired. In this study we have examined the role of wild type LRP6 (LRP6(WT)) and LRP6...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3256876/ https://ncbi.nlm.nih.gov/pubmed/22128165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.295287 |
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