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Low Density Lipoprotein (LDL) Receptor-related Protein 6 (LRP6) Regulates Body Fat and Glucose Homeostasis by Modulating Nutrient Sensing Pathways and Mitochondrial Energy Expenditure

Body fat, insulin resistance, and type 2 diabetes are often linked together, but the molecular mechanisms that unify their association are poorly understood. Wnt signaling regulates adipogenesis, and its altered activity has been implicated in the pathogenesis of type 2 diabetes and metabolic syndro...

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Bibliografische gegevens
Hoofdauteurs: Liu, Wenzhong, Singh, Rajvir, Choi, Cheol Soo, Lee, Hui-Young, Keramati, Ali R., Samuel, Varman T., Lifton, Richard P., Shulman, Gerald I., Mani, Arya
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293520/
https://ncbi.nlm.nih.gov/pubmed/22232553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.286724
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