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Rare nonconservative LRP6 mutations are associated with metabolic syndrome

A rare mutation in LRP6 has been shown to underlie autosomal dominant coronary artery disease (CAD) and metabolic syndrome in an Iranian kindred. The prevalence and spectrum of LRP6 mutations in the disease population of the United States is not known. Two hundred white Americans with early onset fa...

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Autors principals: Singh, Rajvir, Smith, Emily, Fathzadeh, Mohsen, Liu, Wenzhong, Go, Gwang-Woong, Subrahmanyan, Lakshman, Faramarzi, Saeed, McKenna, William, Mani, Arya
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3745535/
https://ncbi.nlm.nih.gov/pubmed/23703864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.22360
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