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Two Lysines in the Forkhead Domain of Foxp3 Are Key to T Regulatory Cell Function
BACKGROUND: The forkhead box transcription factor, Foxp3, is master regulator of the development and function of CD4+CD25+ T regulatory (Treg) cells that limit autoimmunity and maintain immune homeostasis. The carboxyl-terminal forkhead (FKH) domain is required for the nuclear localization and DNA b...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3256141/ https://ncbi.nlm.nih.gov/pubmed/22247766 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029035 |
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