Lack of Association between HLA Class II Alleles and In Vitro Replication Capacities of Recombinant Viruses Encoding HIV-1 Subtype C Gag-Protease from Chronically Infected Individuals

It is unknown whether favorable HLA class II alleles may attenuate HIV-1 through selection pressure in a manner similar to that of protective HLA class I alleles. We investigated the relationship between HLA class II alleles and in vitro replication capacities of recombinant viruses encoding HIV-1 s...

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Detalhes bibliográficos
Main Authors: Wright, Jaclyn K., Brumme, Zabrina L., Julg, Boris, van der Stok, Mary, Mncube, Zenele, Gao, Xiaojiang, Carlson, Jonathan M., Goulder, Philip J. R., Walker, Bruce D., Brockman, Mark A., Ndung'u, Thumbi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255856/
https://ncbi.nlm.nih.gov/pubmed/22090116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06533-11
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