Cross Talk between Immunoglobulin Heavy-Chain Transcription and RNA Surveillance during B Cell Development

Immunoglobulin (Ig) genes naturally acquire frequent premature termination codons during the error-prone V(D)J recombination process. Although B cell differentiation is linked to the expression of productive Ig alleles, the transcriptional status of nonfunctionally recombined alleles remains unclear...

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Main Authors: Tinguely, Aurélien, Chemin, Guillaume, Péron, Sophie, Sirac, Christophe, Reynaud, Stéphane, Cogné, Michel, Delpy, Laurent
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2012
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255717/
https://ncbi.nlm.nih.gov/pubmed/22037763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06138-11
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