AID-induced remodeling of immunoglobulin genes and B cell fate

Survival and phenotype of normal and malignant B lymphocytes are critically dependent on constitutive signals by the B cell receptor (BCR) for antigen. In addition, either antigen ligation of the BCR or various mitogenic stimuli result in B cell activation and induction of activation-induced deamina...

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Autores principales: Laffleur, Brice, Denis-Lagache, Nicolas, Péron, Sophie, Sirac, Christophe, Moreau, Jeanne, Cogné, Michel
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2013
Materias:
Review
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012742/
https://ncbi.nlm.nih.gov/pubmed/24851241
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