Dectin-1-Dependent Interleukin-22 Contributes to Early Innate Lung Defense against Aspergillus fumigatus

We have previously reported that mice deficient in the beta-glucan receptor Dectin-1 displayed increased susceptibility to Aspergillus fumigatus lung infection in the presence of lower interleukin 23 (IL-23) and IL-17A production in the lungs and have reported a role for IL-17A in lung defense. As I...

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Bibliografische gegevens
Hoofdauteurs: Gessner, Melissa A., Werner, Jessica L., Lilly, Lauren M., Nelson, Michael P., Metz, Allison E., Dunaway, Chad W., Chan, Yvonne R., Ouyang, Wenjun, Brown, Gordon D., Weaver, Casey T., Steele, Chad
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2012
Onderwerpen:
Host Response and Inflammation
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255669/
https://ncbi.nlm.nih.gov/pubmed/22038916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05939-11
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