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The beta-glucan receptor Dectin-1 promotes lung immunopathology during fungal allergy via IL-22

Sensitization to fungi, such as the mold Aspergillus fumigatus, is increasingly becoming linked with asthma severity. We have previously shown that lung responses generated via the beta-glucan receptor Dectin-1 are required for lung defense during acute, invasive A. fumigatus infection. Unexpectedly...

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Autori principali: Lilly, Lauren M., Gessner, Melissa A., Dunaway, Chad W., Metz, Allison E., Schweibert, Lisa, Weaver, Casey T., Brown, Gordon D., Steele, Chad
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448838/
https://ncbi.nlm.nih.gov/pubmed/22933634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201797
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