Dectin-1-Dependent Interleukin-22 Contributes to Early Innate Lung Defense against Aspergillus fumigatus

We have previously reported that mice deficient in the beta-glucan receptor Dectin-1 displayed increased susceptibility to Aspergillus fumigatus lung infection in the presence of lower interleukin 23 (IL-23) and IL-17A production in the lungs and have reported a role for IL-17A in lung defense. As I...

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Autors principals: Gessner, Melissa A., Werner, Jessica L., Lilly, Lauren M., Nelson, Michael P., Metz, Allison E., Dunaway, Chad W., Chan, Yvonne R., Ouyang, Wenjun, Brown, Gordon D., Weaver, Casey T., Steele, Chad
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
Matèries:
Host Response and Inflammation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255669/
https://ncbi.nlm.nih.gov/pubmed/22038916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05939-11
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