Dectin-1-Dependent Interleukin-22 Contributes to Early Innate Lung Defense against Aspergillus fumigatus

We have previously reported that mice deficient in the beta-glucan receptor Dectin-1 displayed increased susceptibility to Aspergillus fumigatus lung infection in the presence of lower interleukin 23 (IL-23) and IL-17A production in the lungs and have reported a role for IL-17A in lung defense. As I...

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Autori principali: Gessner, Melissa A., Werner, Jessica L., Lilly, Lauren M., Nelson, Michael P., Metz, Allison E., Dunaway, Chad W., Chan, Yvonne R., Ouyang, Wenjun, Brown, Gordon D., Weaver, Casey T., Steele, Chad
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2012
Soggetti:
Host Response and Inflammation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255669/
https://ncbi.nlm.nih.gov/pubmed/22038916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05939-11
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