Mouse Models for Down Syndrome-Associated Developmental Cognitive Disabilities

Down syndrome (DS) is mainly caused by the presence of an extra copy of human chromosome 21 (Hsa21) and is a leading genetic cause for developmental cognitive disabilities in humans. The mouse is a premier model organism for DS because the regions on Hsa21 are syntenically conserved with three regio...

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Detalhes bibliográficos
Main Authors: Liu, Chunhong, Belichenko, Pavel V., Zhang, Li, Fu, Dawei, Kleschevnikov, Alexander M., Baldini, Antonio, Antonarakis, Stylianos E., Mobley, William C., Yu, Y. Eugene
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2011
Assuntos:
Down Syndrome/Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3254039/
https://ncbi.nlm.nih.gov/pubmed/21865664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000329422
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