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Identification of the heparin binding site on adeno-associated virus serotype 3B (AAV-3B)
Adeno-associated virus is a promising vector for gene therapy. In the current study, the binding site on AAV serotype 3B for the heparan sulfate proteoglycan (HSPG) receptor has been characterized. X-ray diffraction identified a disaccharide binding site at the most positively charged region on the...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3253896/ https://ncbi.nlm.nih.gov/pubmed/22169623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2011.10.007 |
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