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The use of Bcl-2 over-expression to stabilize hybridomas specific to the HERG potassium channel

We encountered a high degree of clonal hybridoma loss in the course of generating antibodies specific for the hERG potassium channel a protein that is crucial for controlling heart rhythm, is abundant in parts of the brain and is abnormally expressed in some tumors. Intracellular domains of the prot...

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Detalhes bibliográficos
Main Authors: Sroubek, Jakub, Krishnan, Yamini, Chinai, Jordan, Buhl, Susan, Scharff, Matthew D., McDonald, Thomas V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253882/
https://ncbi.nlm.nih.gov/pubmed/22107967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2011.10.014
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