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The use of Bcl-2 over-expression to stabilize hybridomas specific to the HERG potassium channel
We encountered a high degree of clonal hybridoma loss in the course of generating antibodies specific for the hERG potassium channel a protein that is crucial for controlling heart rhythm, is abundant in parts of the brain and is abnormally expressed in some tumors. Intracellular domains of the prot...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3253882/ https://ncbi.nlm.nih.gov/pubmed/22107967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2011.10.014 |
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