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Protein Kinase A Activity at the Endoplasmic Reticulum Surface Is Responsible for Augmentation of Human ether-a-go-go-related Gene Product (HERG)

Human ether-a-go-go-related gene product (HERG) is a cardiac potassium channel commonly implicated in the pathogenesis of the long QT syndrome, type 2 (LQT2). LQT2 mutations typically have incomplete penetrance and affect individuals at various stages of their lives; this may mirror variations in in...

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Detalhes bibliográficos
Main Authors: Sroubek, Jakub, McDonald, Thomas V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122247/
https://ncbi.nlm.nih.gov/pubmed/21536683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.201699
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