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Mechanisms underlying the protein-kinase mediated regulation of the HERG potassium channel synthesis

The HERG (human ether-a-go-go related gene) potassium channel aids in repolarization of the cardiomyocyte membrane at the end of each action potential. We have previously shown that sustained protein kinase A or C (PKA and PKC) activity specifically enhances channel synthesis over the course of hour...

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Detalhes bibliográficos
Main Authors: Krishnan, Yamini, Li, Yan, Zheng, Renjian, Kanda, Vikram, McDonald, Thomas V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398701/
https://ncbi.nlm.nih.gov/pubmed/22613764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2012.05.012
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