טוען...
The receptor tyrosine kinase ErbB3 maintains the balance between luminal and basal breast epithelium
ErbB3 harbors weak kinase activity, but strongly activates downstream phosphatidylinositol 3-kinase/Akt signaling through heterodimerization with and activation by other ErbB receptor tyrosine kinases. We report here that ErbB3 loss in the luminal mammary epithelium of mice impaired Akt and MAPK sig...
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Main Authors: | , , , , , , , , , , , , |
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פורמט: | Artigo |
שפה: | Inglês |
יצא לאור: |
National Academy of Sciences
2012
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נושאים: | |
גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3252958/ https://ncbi.nlm.nih.gov/pubmed/22178756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1115802109 |
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