ErbB3 drives mammary epithelial survival and differentiation during pregnancy and lactation

BACKGROUND: During pregnancy, as the mammary gland prepares for synthesis and delivery of milk to newborns, a luminal mammary epithelial cell (MEC) subpopulation proliferates rapidly in response to systemic hormonal cues that activate STAT5A. While the receptor tyrosine kinase ErbB4 is required for...

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Détails bibliographiques
Publié dans:Breast Cancer Res
Auteurs principaux: Williams, Michelle M., Vaught, David B., Joly, Meghan Morrison, Hicks, Donna J., Sanchez, Violeta, Owens, Philip, Rahman, Bushra, Elion, David L., Balko, Justin M., Cook, Rebecca S.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5591538/
https://ncbi.nlm.nih.gov/pubmed/28886748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-017-0893-7
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