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The proteasomal subunit Rpn6 is a molecular clamp holding the core and regulatory subcomplexes together
Proteasomes execute the degradation of most cellular proteins. Although the 20S core particle (CP) has been studied in great detail, the structure of the 19S regulatory particle (RP), which prepares ubiquitylated substrates for degradation, has remained elusive. Here, we report the crystal structure...
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| Main Authors: | , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3252951/ https://ncbi.nlm.nih.gov/pubmed/22187461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117648108 |
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