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Crystal structure of the proteasomal deubiquitylation module Rpn8-Rpn11
The ATP-dependent degradation of polyubiquitylated proteins by the 26S proteasome is essential for the maintenance of proteome stability and the regulation of a plethora of cellular processes. Degradation of substrates is preceded by the removal of polyubiquitin moieties through the isopeptidase act...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3939901/ https://ncbi.nlm.nih.gov/pubmed/24516147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1400546111 |
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