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In Vivo and In Vitro Pharmacological Studies of Methoxycarbonyl-Carboetomidate

BACKGROUND: We previously developed two etomidate analogs that retain etomidate’s favorable hemodynamic properties, but whose adrenocortical effects are reduced in duration or magnitude. Methoxycarbonyl-etomidate (MOC-etomidate) is rapidly metabolized and ultra-short acting whereas (R)-ethyl 1-(1-ph...

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Bibliographische Detailangaben
Hauptverfasser: Pejo, Ervin, Cotten, Joseph F., Kelly, Elizabeth W., Ge, Ri Le, Cuny, Gregory D., Laha, Joydev K., Liu, Jifeng, Lin, Xiang Jie, Raines, Douglas E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3252484/
https://ncbi.nlm.nih.gov/pubmed/21965364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0b013e3182320559
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