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A Mathematical Methodology for Determining the Temporal Order of Pathway Alterations Arising during Gliomagenesis
Human cancer is caused by the accumulation of genetic alterations in cells. Of special importance are changes that occur early during malignant transformation because they may result in oncogene addiction and thus represent promising targets for therapeutic intervention. We have previously described...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3252265/ https://ncbi.nlm.nih.gov/pubmed/22241976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002337 |
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