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Fitness costs limit influenza A virus hemagglutinin glycosylation as an immune evasion strategy
Here, we address the question of why the influenza A virus hemagglutinin (HA) does not escape immunity by hyperglycosylation. Uniquely among dozens of monoclonal antibodies specific for A/Puerto Rico/8/34, escape from H28-A2 neutralization requires substitutions introducing N-linked glycosylation at...
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| Hoofdauteurs: | , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
2011
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3251056/ https://ncbi.nlm.nih.gov/pubmed/22106257 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1108754108 |
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