Estrogen Receptor-Beta Variants Are Associated with Increased Risk of Alzheimer's Disease in Women with Down Syndrome

BACKGROUND/AIMS: Genetic variants that affect estrogen activity may influence the risk of Alzheimer's disease (AD). We examined the relation of polymorphisms in the gene for the estrogen receptor-beta (ESR2) to the risk of AD in women with Down syndrome. METHODS: Two hundred and forty-nine wome...

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Detalhes bibliográficos
Main Authors: Zhao, Qi, Lee, Joseph H., Pang, Deborah, Temkin, Alexis, Park, Naeun, Janicki, Sarah C., Zigman, Warren B., Silverman, Wayne, Tycko, Benjamin, Schupf, Nicole
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2012
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Original Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250648/
https://ncbi.nlm.nih.gov/pubmed/22156442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000334522
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