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Estrogen Receptor-α variants increase risk of Alzheimer’s Disease in women with Down syndrome
BACKGROUND: Genetic variants that affect estrogen activity may influence the risk of Alzheimer’s disease (AD). Two tightly linked polymorphisms (PvuII and XbaI) in the first intron of estrogen receptor 1 (ESR1), the gene for ER-α, have been reported to influence estrogen receptor expression and may...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2430887/ https://ncbi.nlm.nih.gov/pubmed/18408366 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000126495 |
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