Association between Genetic Variants in Sortilin-Related Receptor 1 (SORL1) and Alzheimer's Disease in Adults with Down syndrome

Recent reports have suggested that variants in the sortilin-related receptor gene (SORL1) increase the risk of late onset Alzheimer's disease (AD) in Northern European, Hispanic, African-American and Isreali-Arab populations. SORL1 directs trafficking of amyloid precursor protein (APP) and unde...

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Detalhes bibliográficos
Main Authors: Lee, Joseph. H., Chulikavit, Maruit, Pang, Deborah, Zigman, Warren B., Silverman, Wayne, Schupf, Nicole
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2131721/
https://ncbi.nlm.nih.gov/pubmed/17826910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2007.08.042
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