Glucose-Induced O(2) Consumption Activates Hypoxia Inducible Factors 1 and 2 in Rat Insulin-Secreting Pancreatic Beta-Cells

BACKGROUND: Glucose increases the expression of glycolytic enzymes and other hypoxia-response genes in pancreatic beta-cells. Here, we tested whether this effect results from the activation of Hypoxia-Inducible-factors (HIF) 1 and 2 in a hypoxia-dependent manner. METHODOLOGY/PRINCIPAL FINDINGS: Isol...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bensellam, Mohammed, Duvillié, Bertrand, Rybachuk, Galyna, Laybutt, D. Ross, Magnan, Christophe, Guiot, Yves, Pouysségur, Jacques, Jonas, Jean-Christophe
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2012
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250482/
https://ncbi.nlm.nih.gov/pubmed/22235342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029807
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak