Phlda3 regulates beta cell survival during stress

The loss of functional beta cell mass characterises all forms of diabetes. Beta cells are highly susceptible to stress, including cytokine, endoplasmic reticulum (ER) and oxidative stress. This study examined the role of pleckstrin homology-like, domain family A, member 3 (Phlda3) in beta cell survi...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Bensellam, Mohammed, Chan, Jeng Yie, Lee, Kailun, Joglekar, Mugdha V., Hardikar, Anandwardhan A., Loudovaris, Thomas, Thomas, Helen E., Jonas, Jean-Christophe, Laybutt, D. Ross
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731300/
https://ncbi.nlm.nih.gov/pubmed/31492921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49289-5
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