Oncolytic Virus-Mediated Manipulation of DNA Damage Responses: Synergy With Chemotherapy in Killing Glioblastoma Stem Cells

BACKGROUND: Although both the alkylating agent temozolomide (TMZ) and oncolytic viruses hold promise for treating glioblastoma, which remains uniformly lethal, the effectiveness of combining the two treatments and the mechanism of their interaction on cancer stem cells are unknown. METHODS: We inves...

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Detaylı Bibliyografya
Asıl Yazarlar: Kanai, Ryuichi, Rabkin, Samuel D., Yip, Stephen, Sgubin, Donatella, Zaupa, Cecile M., Hirose, Yuichi, Louis, David N., Wakimoto, Hiroaki, Martuza, Robert L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2012
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250384/
https://ncbi.nlm.nih.gov/pubmed/22173583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djr509
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