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Mutant Huntingtin, Abnormal Mitochondrial Dynamics, Defective Axonal Transport of Mitochondria, and Selective Synaptic Degeneration in Huntington’s Disease
Huntington’s disease (HD) is a progressive, fatal neurodegenerative disease caused by an expanded polyglutamine repeats in the HD gene. HD is characterized by chorea, seizures, involuntary movements, dystonia, cognitive decline, intellectual impairment and emotional disturbances. Research into mutan...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3249480/ https://ncbi.nlm.nih.gov/pubmed/22080977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2011.10.016 |
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