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Superoxide dismutase 1 encoding mutations linked to ALS adopts a spectrum of misfolded states

BACKGROUND: Mutations in superoxide dismutase 1 (SOD1), which are one cause of familial amyotrophic lateral sclerosis (fALS), induce misfolding and aggregation of the protein. Misfolding can be detected by the binding of antibodies raised against peptide epitopes that are normally buried in the nati...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Prudencio, Mercedes, Borchelt, David R
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248846/
https://ncbi.nlm.nih.gov/pubmed/22094223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-6-77
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