Cargando...

Superoxide dismutase 1 encoding mutations linked to ALS adopts a spectrum of misfolded states

BACKGROUND: Mutations in superoxide dismutase 1 (SOD1), which are one cause of familial amyotrophic lateral sclerosis (fALS), induce misfolding and aggregation of the protein. Misfolding can be detected by the binding of antibodies raised against peptide epitopes that are normally buried in the nati...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Prudencio, Mercedes, Borchelt, David R
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248846/
https://ncbi.nlm.nih.gov/pubmed/22094223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-6-77
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!