Structural interconversions modulate activity of Escherichia coli ribonucleotide reductase

Essential for DNA biosynthesis and repair, ribonucleotide reductases (RNRs) convert ribonucleotides to deoxyribonucleotides via radical-based chemistry. Although long known that allosteric regulation of RNR activity is vital for cell health, the molecular basis of this regulation has been enigmatic,...

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Detalhes bibliográficos
Main Authors: Ando, Nozomi, Brignole, Edward J., Zimanyi, Christina M., Funk, Michael A., Yokoyama, Kenichi, Asturias, Francisco J., Stubbe, JoAnne, Drennan, Catherine L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248520/
https://ncbi.nlm.nih.gov/pubmed/22160671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1112715108
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