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Structural interconversions modulate activity of Escherichia coli ribonucleotide reductase
Essential for DNA biosynthesis and repair, ribonucleotide reductases (RNRs) convert ribonucleotides to deoxyribonucleotides via radical-based chemistry. Although long known that allosteric regulation of RNR activity is vital for cell health, the molecular basis of this regulation has been enigmatic,...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3248520/ https://ncbi.nlm.nih.gov/pubmed/22160671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1112715108 |
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