The population pharmacokinetics of R- and S-warfarin: effect of genetic and clinical factors

BACKGROUND: Warfarin is a drug with a narrow therapeutic index and large interindividual variability in daily dosing requirements. Patients commencing warfarin treatment are at risk of bleeding due to excessive anticoagulation caused by overdosing. The interindividual variability in dose requirement...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Lane, Steven, Al-Zubiedi, Sameh, Hatch, Ellen, Matthews, Ivan, Jorgensen, Andrea L, Deloukas, Panos, Daly, Ann K, Park, B Kevin, Aarons, Leon, Ogungbenro, Kayode, Kamali, Farhad, Hughes, Dyfrig, Pirmohamed, Munir
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2012
Matèries:
Pharmacokinetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248257/
https://ncbi.nlm.nih.gov/pubmed/21692828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2011.04051.x
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars