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Insights into 4E-BP1 and p53 mediated regulation of accelerated cell senescence

Senescence is a valid tumor suppressive mechanism in cancer. Accelerated cell senescence describes the growth arrested state of cells that have been treated with anti-tumor drugs, such as doxorubicin that induce a DNA damage response. Discodermolide, a microtubule-stabilizing agent, is a potent indu...

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Detalles Bibliográficos
Main Authors: Chao, Suzan K., Horwitz, Susan Band, McDaid, Hayley M.
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248149/
https://ncbi.nlm.nih.gov/pubmed/21399233
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