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Transgenic inhibition of Nogo-66 receptor function allows axonal sprouting and improved locomotion after spinal injury

Axon growth after spinal injury is thought to be limited in part by myelin-derived proteins that act via the Nogo-66 Receptor (NgR). To test this hypothesis, we sought to study recovery from spinal cord injury (SCI) after inhibiting NgR transgenically with a soluble function-blocking NgR fragment. G...

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Detaylı Bibliyografya
Asıl Yazarlar: Li, Shuxin, Kim, Ji-Eun, Budel, Stephane, Hampton, Thomas G., Strittmatter, Stephen M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2005
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3246391/
https://ncbi.nlm.nih.gov/pubmed/15866044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2004.12.008
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