Blockade of Nogo-66, Myelin-Associated Glycoprotein, and Oligodendrocyte Myelin Glycoprotein by Soluble Nogo-66 Receptor Promotes Axonal Sprouting and Recovery after Spinal Injury

The growth of injured axons in the adult mammalian CNS is limited after injury. Three myelin proteins, Nogo, MAG (myelin-associated glycoprotein), and OMgp (oligodendrocyte myelin glycoprotein), bind to the Nogo-66 receptor (NgR) and inhibit axonal growth in vitro. Transgenic or viral blockade of Ng...

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Bibliografische gegevens
Gepubliceerd in:J Neurosci
Hoofdauteurs: Li, Shuxin, Liu, Betty P., Budel, Stephane, Li, Mingwei, Ji, Benxiu, Walus, Lee, Li, Weiwei, Jirik, Adrienna, Rabacchi, Sylvia, Choi, Eugene, Worley, Dane, Sah, Dinah W. Y., Pepinsky, Blake, Lee, Daniel, Relton, Jane, Strittmatter, Stephen M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2004
Onderwerpen:
Development/Plasticity/Repair
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6730300/
https://ncbi.nlm.nih.gov/pubmed/15548666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2828-04.2004
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