Mutation Rate Inferred From Synonymous Substitutions in a Long-Term Evolution Experiment With Escherichia coli

The quantification of spontaneous mutation rates is crucial for a mechanistic understanding of the evolutionary process. In bacteria, traditional estimates using experimental or comparative genetic methods are prone to statistical uncertainty and consequently estimates vary by over one order of magn...

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Autores principales: Wielgoss, Sébastien, Barrick, Jeffrey E., Tenaillon, Olivier, Cruveiller, Stéphane, Chane-Woon-Ming, Béatrice, Médigue, Claudine, Lenski, Richard E., Schneider, Dominique
Formato: Artigo
Lenguaje:Inglês
Publicado: Genetics Society of America 2011
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Investigation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3246271/
https://ncbi.nlm.nih.gov/pubmed/22207905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.111.000406
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