Mutation rate dynamics in a bacterial population reflect tension between adaptation and genetic load

Mutations are the ultimate source of heritable variation for evolution. Understanding how mutation rates themselves evolve is thus essential for quantitatively understanding many evolutionary processes. According to theory, mutation rates should be minimized for well-adapted populations living in st...

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Bibliographic Details
Main Authors: Wielgoss, Sébastien, Barrick, Jeffrey E., Tenaillon, Olivier, Wiser, Michael J., Dittmar, W. James, Cruveiller, Stéphane, Chane-Woon-Ming, Béatrice, Médigue, Claudine, Lenski, Richard E., Schneider, Dominique
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2013
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538217/
https://ncbi.nlm.nih.gov/pubmed/23248287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1219574110
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