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Conditional disruption of IκB kinase 2 fails to prevent obesity-induced insulin resistance
The inhibitor of NF-κB (IκB) kinases (IKK1[α] and IKK2[β]), the catalytic subunits of the IKK complex, phosphorylate IκB proteins on serine residues, targeting them for degradation and thus activating the transcription factor NF-κB. More recently, IKK2 has been implicated in mediation of insulin res...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Clinical Investigation
2004
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC324533/ https://ncbi.nlm.nih.gov/pubmed/14755344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200418712 |
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