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Activation of Autophagy Protects against Acetaminophen-Induced Hepatotoxicity
Autophagy can selectively remove damaged organelles, including mitochondria, and in turn protect against mitochondria damage induced-cell death. Acetaminophen (APAP) overdose can cause liver injury in animals and humans by inducing mitochondria damage and subsequent necrosis in hepatocytes. Although...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3245329/ https://ncbi.nlm.nih.gov/pubmed/21932416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24690 |
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