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Major differences in the responses of primary human leukocyte subsets to IFN-β()
Treatment of cell lines with type I IFNs activates the formation of ISGF3 (STAT1/STAT2/IRF9), which induces the expression of many genes. To study this response in primary cells, we treated fresh human blood with IFN-β and used flow cytometry to analyze phosphorylated STATs1, 3 and 5 in CD4(+) and C...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3244975/ https://ncbi.nlm.nih.gov/pubmed/20956346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902314 |
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