Excessive Biologic Response to IFNβ Is Associated with Poor Treatment Response in Patients with Multiple Sclerosis

BACKGROUND: Interferon-beta (IFNβ) is used to inhibit disease activity in multiple sclerosis (MS), but its mechanisms of action are incompletely understood, individual treatment response varies, and biological markers predicting response to treatment have yet to be identified. METHODS: The relations...

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Bibliographic Details
Main Authors: Rudick, Richard A., Rani, M. R. Sandhya, Xu, Yaomin, Lee, Jar-Chi, Na, Jie, Shrock, Jennifer, Josyula, Anupama, Fisher, Elizabeth, Ransohoff, Richard M.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094352/
https://ncbi.nlm.nih.gov/pubmed/21602934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019262
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