The role of cell type-specific responses in IFN-β therapy of multiple sclerosis

The mechanism of IFN-β therapy in relapsing-remitting multiple sclerosis (RRMS) is not well understood, but induction of apoptosis in specific leukocyte subsets is likely to be important. Enhanced expression of TNFSF10 or TNF-related apoptosis-inducing ligand (TRAIL) mRNA in unseparated leukocytes h...

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Bibliographic Details
Main Authors: Zula, Joana A., Green, Holly C., Ransohoff, Richard M., Rudick, Richard A., Stark, George R., van Boxel-Dezaire, Anette H. H.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2011
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241780/
https://ncbi.nlm.nih.gov/pubmed/22106296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117347108
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