Cooperation of the HDAC inhibitor vorinostat and radiation in metastatic neuroblastoma: Efficacy and underlying mechanisms

Histone deacetylase (HDAC) inhibitors can radiosensitize cancer cells. Radiation is critical in high-risk neuroblastoma treatment, and combinations of HDAC inhibitor vorinostat and radiation are proposed for neuroblastoma trials. Therefore, we investigated radiosensitizing effects of vorinostat in n...

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Detalhes bibliográficos
Main Authors: Mueller, Sabine, Yang, Xiaodong, Sottero, Theo L., Gragg, Ashley, Prasad, Gautam, Polley, Mei-Yin, Weiss, William A., Matthay, Katherine K., Davidoff, Andrew M., DuBois, Steven G., Haas-Kogan, Daphne A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244077/
https://ncbi.nlm.nih.gov/pubmed/21497989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2011.03.010
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