Vorinostat increases expression of functional norepinephrine transporter in neuroblastoma in vitro and in vivo model systems

PURPOSE: Histone deacetylase (HDAC) inhibition causes transcriptional activation or repression of several genes that in turn can influence the biodistribution of other chemotherapeutic agents. Here, we hypothesize that the combination of vorinostat, a HDAC inhibitor, with (131)I-metaiodobenzylguanid...

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Bibliografische gegevens
Hoofdauteurs: More, Swati S., Itsara, Melissa, Yang, Xiaodong, Geier, Ethan G., Tadano, Michelle K., Seo, Youngho, VanBrocklin, Henry F., Weiss, William A., Mueller, Sabine, Haas-Kogan, Daphne A., DuBois, Steven G., Matthay, Katherine K., Giacomini, Kathleen M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3247296/
https://ncbi.nlm.nih.gov/pubmed/21421857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-2949
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